Arizona is much different than Manchin's West Virginia, where that question is legitimate. Arizona is purple, West Virginia as deep a red as you can get. It's hard to imagine anyone further left than Manchin occupying his seat.
Another difference: Didn't Sinema run in the primaries as a progressive? I honestly can't remember, but I thought she did. So she is not legitimately representing the people who originally voted for her. It's like a bait and switch.